Key Products

BFS Molecular provides a new breed of post-transplant monitoring tests, using the latest in NGS (Next Generation Sequencing) technology on the reliable and scalable Illumina platforms - and offering novel approaches and a higher quality of results than anything available today.

We have adopted an integrated approach to monitoring, offering a single software package called Graftrack™ covering the whole continuum of post-transplant testing, and providing streamlined workflows for transplantation testing labs - to save time, effort and money.

 

 
 

chimerism monitoring

StemScan™ offers sensitive, comprehensive and consistent post-transplant chimerism detection for allogeneic HSCT (Hematopoietic Stem Cell Transplant) patients using NGS data.

The easy to use batch workflow makes it straightforward to process many samples simultaneously in the lab. 

Organ monitoring

OrganScan™ offers sensitive donor-derived DNA detection post-transplant for solid organ transplant patients using NGS data .

An increasing proportion of donor-derived DNA in the cell-free DNA (cfDNA) population of the recipient is an early indicator of damage to the graft, and can be detected non-invasively via a simple blood test. 

monitoring software

NGS tests produce huge amounts of data, so a vital component of StemScan™ and OrganScan™ is the Graftrack™ software.

Providing a holistic approach to all kinds of post-transplant monitoring, Graftrack™ allows entry of other monitoring results alongside those for StemScan™ or OrganScan™, producing a comprehensive picture of each recipient over time. 

 
 

Flexibility & Simplicity

“The most vital thing for me is how many lab techs I have routinely performing labor-intensive tests, day in, day out... I need to free them up for more productive activities.“ 

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Quality & Reliability

Manufactured in the UK, all StemScan™ and OrganScan™ assay components additionally undergo a rigorous quality control by NGS before being released.

Graftrack™ measures and reports over 20 quality metrics, performs quality and adaptor trimming automatically, and performs a dual analysis for additional confidence in the results, using both the ’raw’ sequencing data and the ’consensus’ data generated using unique molecular indexes.